Do I need a Post-Cycle Therapy (PCT) after cycling LGD 4033? Yes, Ligandrol has a slightly suppressive action on the Hypothalamic Pituitary Testicular Axis (HPTA), mk 2866 supplement. As a result, you might experience low testosterone symptoms in the four weeks to eight weeks following the end of your cycle. An OTC PCT like a test-booster will be sufficient for speeding up your recovery of the HPTA to normal levels. DISCLAIMER: The publishing website and author bear no onus of responsibility for your use of SARMs.Anabolic steroids and SARMs decrease endogenous testosterone levels, caused by overstimulation of the androgen receptor, mk 2866 supplement.